Archive tagged cytokines

THE ROLE OF INFLAMMATORY MARKERS IN DISODERS OF BONE REMODELLING

The role of receptor antagonist interleukin and galectin-3 in the regulation of bone remodeling processes in the experiment was studied. In the experimental groups of animals had a decrease in bone density compared with the control group. In the blood serum of experimental animals was observed an imbalance of the levels of pro- and anti-inflammatory […]

АPPLICATION OF INTERFERON INDUCERS (CYCLOFERON) IN THE THERAPY PROTOCOLS FOR CHILDREN WITH BRONCHIAL ASTHMA

A promising direction in improving the methods of treatment of asthma in children is to include in the protocol the basic treatment of immunomo- dulatory drugs. Purpose — to estimate immunomo- dulatory properties of interferon inducer (cyclofe- ron) in the protocol treatment of asthma in children. The results of research — the use of interferon […]

TO THE QUESTION ABOUT THE ROLE OF THE FUNCTIONAL STATE OF THE CONNECTIVE TISSUE IN THE REALIZATION OF THE SYSTEMIC RESPONSE TO INJURY

On the basis of General provisions on the functio­nal system of connective tissue, inflammatory-reparative response as the stereotypical response to injury, given the adaptive reserves of the connective tissue are considered questions of the intercellular interactions and imbalance in the system of cytokines. Modern ideas about the origin and functions of cells fibroblastic series (progenitor […]

Experimental and clinical substantiation bronchoconstrictor properties of inflammatory cytokines in children with asthma

In the pathogenesis of asthma in children, regardless of the etiology of the case features of an autoimmune component triggering the production sensitized T-lymphocytes inflammatory cytokines cause the development of chronic allergic inflammation in the broncho-pulmonary system. Purpose — to study experimentally proinflammatory cytokines sensitized T-lymphocytes that have bronchoconstrictor properties. Results Stu­dies — on the […]

Mechanisms of metabolic disorders of bone tissue in kidney disease development

Currently, much attention is paid to the search for markers of acute and chronic renal failure that allow having early detection of pathological changes in the kidneys. However it is important to consider that for treatment of diseases of kidneys, glucocorticoids are widely used. However they strongly change balance of cytokines that can leads to […]

Charecteristic of cytokine metabolism in patients with purulent bacterial meningitis

In patients with purulent bacterial meningitis in dynamics of a disease the increase in level of proinfl ammatory (IL-1, IL-2, IL-6, FNO-α) and antiinfl ammatory (IL-4, IL-10) cytokines in comparison with control, and also an imbalance in favor of domination of activity of pro-infl ammatory cytokines in relation to anti-infl ammatory is noted that causes […]

Proinflammatory factors as predictors of arrhythmia recurrence in patients with coronary heart disease combined with hypertension and persistent atrial fibrillation

Atrial fibrillation remains a serious and unresolved problem, whereby propagation of thisdisease makes 1–2 % in the population and leads todisability. In order to assess the predictor value of the left atrium linear dimensions as for the recurrence of arrhythmia, cytokines (IL-1β, TNF-α) andendothelin-1 in patients with coronary heart desease combined with II stage hypertension and persistentatrial […]