Статьи с метками cytokines

VIOLATION OF THE FUNCTIONAL STATE OF CONNECTIVE TISSUE AS PART OF THE PATHOLOGICAL PROCESS

PUMTS. 2020; 37(1): 62-66. https://doi.org/10.31071/promedosvity2020.01.062 The article shows that the reaction of the physiological system of connective tissue (CT) plays a key role in the reaction of the macroorganism to damage, which ultimately determines the adaptive capabilities of the body. Modern achievements of fundamental Sciences and practical medicine indicate that although the pathological processes of […]

THE ROLE OF PRO-INFLAMMATORY CYTOKINES IN ACTIVATION LATENT INTRACELLULAR INFECTION IN AUTOIMMUNE RHEUMATIC DISEASES AND TUBERCULOSIS

PUMTS. 2019; 36(4): 49-55. https://doi.org/10.31071/promedosvity2019.04.049 Full text (PDF) According to the modern concept, the leading role in the development of autoimmune rheumatic diseases along with auto-reactive clones of T- and B-lymphocytes is played by mediators of intercellular interaction — cytokines. The leading role of cytokines in the pathogenesis of human disease is discussed in the […]

STATUS OF CYTOCINES OF CHILDREN WITH CHRONIC WEB-INFECTION BEFORE AND AFTER REVACATION OF THE MEASLES

PUMTS. 2018; 32(4): 83-87 https://doi.org/10.31071/promedosvity2018.04.083 Effective vaccination against measles of children with chronic herpesvirus infection is actual problem, especially during the period of growing incidence of measles in Ukraine. In 68 children with chronic VEB-infection was studied the influence of cytokines on the production of protective IgG against measles virus after revaccination with the Priorix […]

THE ROLE OF INFLAMMATORY MARKERS IN DISODERS OF BONE REMODELLING

PUMTS. 2017; 25(2): 49-53. https://doi.org/10.31071/promedosvity2017.02.049 The role of receptor antagonist interleukin and galectin-3 in the regulation of bone remodeling processes in the experiment was studied. In the experimental groups of animals had a decrease in bone density compared with the control group. In the blood serum of experimental animals was observed an imbalance of the […]

АPPLICATION OF INTERFERON INDUCERS (CYCLOFERON) IN THE THERAPY PROTOCOLS FOR CHILDREN WITH BRONCHIAL ASTHMA

PUMTS. 2017; 25(2): 39-48. https://doi.org/10.31071/promedosvity2017.02.039 A promising direction in improving the methods of treatment of asthma in children is to include in the protocol the basic treatment of immunomo- dulatory drugs. Purpose — to estimate immunomo- dulatory properties of interferon inducer (cyclofe- ron) in the protocol treatment of asthma in children. The results of research […]

TO THE QUESTION ABOUT THE ROLE OF THE FUNCTIONAL STATE OF THE CONNECTIVE TISSUE IN THE REALIZATION OF THE SYSTEMIC RESPONSE TO INJURY

On the basis of General provisions on the functio­nal system of connective tissue, inflammatory-reparative response as the stereotypical response to injury, given the adaptive reserves of the connective tissue are considered questions of the intercellular interactions and imbalance in the system of cytokines. Modern ideas about the origin and functions of cells fibroblastic series (progenitor […]

Experimental and clinical substantiation bronchoconstrictor properties of inflammatory cytokines in children with asthma

In the pathogenesis of asthma in children, regardless of the etiology of the case features of an autoimmune component triggering the production sensitized T-lymphocytes inflammatory cytokines cause the development of chronic allergic inflammation in the broncho-pulmonary system. Purpose — to study experimentally proinflammatory cytokines sensitized T-lymphocytes that have bronchoconstrictor properties. Results Stu­dies — on the […]