Archive tagged bronchial asthma

PRINCIPLES OF IMMUNOCORRECTIVE THERAPY IN CHILDREN WITH BRONCHIAL ASTHMA

The paper presents data on the use of immunocorrective therapy in children with bronchial asthma with isolated autoantibodies from H1-blockers of histamine of the first generation with taewegil and suprastin, which removes autoimmune reactions in the bronchopulmonary system by inhibiting the action of anti-idiotypic antibodies. The effect of immunocorrective therapy did not depend on the […]

THE EFFECT OF PENTOXIFYLLINE (TRENTAL) ON THE PRODUCTION OF CYTOKINES WITH SENSITIZED T-LYMPHOCYTES IN BRONCHIAL ASTHMA IN CHILDREN

At the present stage of the development of the problem in the pathogenesis of bronchial asthma, the proinflammatory cytokines of sensitized T-­lymphocytes TNF-α, IL­-4, IL-­1β are increasing in importance in the blood serum level from light to severe bronchial asthma. The immune system controls the antibodies of these cytokines, the reliability of which is determined […]

АPPLICATION OF INTERFERON INDUCERS (CYCLOFERON) IN THE THERAPY PROTOCOLS FOR CHILDREN WITH BRONCHIAL ASTHMA

A promising direction in improving the methods of treatment of asthma in children is to include in the protocol the basic treatment of immunomo- dulatory drugs. Purpose — to estimate immunomo- dulatory properties of interferon inducer (cyclofe- ron) in the protocol treatment of asthma in children. The results of research — the use of interferon […]

IMMUNOLOGICAL CONTROL OF INFLAMMATORY CYTOKINES IN CHILDREN WITH ASTHMA

In immunogenesis asthma in children are increa­ singly paying attention to the researchers cytokines sensitized T lymphocyte — tumor necrosis factor — a (TNF-α), interleukin 4 (IL-4) and interleukin 1b (IL-1b). Hyperproduction these cytokines in the body of children with asthma, according to the physiological mechanisms should be regulated by the immune system itself, its […]

Experimental and clinical substantiation bronchoconstrictor properties of inflammatory cytokines in children with asthma

In the pathogenesis of asthma in children, regardless of the etiology of the case features of an autoimmune component triggering the production sensitized T-lymphocytes inflammatory cytokines cause the development of chronic allergic inflammation in the broncho-pulmonary system. Purpose — to study experimentally proinflammatory cytokines sensitized T-lymphocytes that have bronchoconstrictor properties. Results Stu­dies — on the […]

Methyl and halogen glucocorticosteroids and related antimicrobial properties against microorganisms isolated from the sputum of children with bronchial asthma

Related studied antimicrobial properties of glucocorticosteroids — prednisolone, methylprednisolone, dexamethasone, polkortolone, beclomethasone dipropionate, fl uticasone propionate against microorganisms isolated from the sputum of 135 children with bronchial asthma at the age of 11 ± 0,12 years.

Slower hypersensitivity reaction in children with bronchial asthma

In this issue there are shown the features of marker activities of cellular immunity in children with В A. It is done in a pretty factual material. The changes are discovered in hyposupressive type of markers CD3, CD8, B-lymphocytes — CD19 and the increase of CD95 Shown changes are pathogenetic basis for the development of […]