THE IMPACT OF IMMUNE MECHANISMS IN THE PATHOGENESIS OF CHRONIC APICAL PERIODONTITIS

PUMTS. 2019; 36(4): 56-59.
https://doi.org/10.31071/promedosvity2019.04.056

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In this paper the development of odontogenic foci of infection in the form of various nosological forms of chronic periodontitis is highlighted and observed in persons with general somatic diseases, which may be accompanied by changes in indicators of immunity at the general and local levels. It should be noted that the chronicity of the inflammatory process in the periodontium is a complex immunopathological process, which is influenced by the functional activity of immunocompetent cells, the production of certain immunoglobulins, cytokines, pathogenetic immune complexes and adhesive molecules and the like. The authors have proved the need for a detailed study of the immunopathological development of inflammation in the surrounding apical tissues of the teeth, T and B cell level of local immunity, for the purpose of correct pathogenetic treatment for the preservation of teeth with chronic apical periodontitis.

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