INSOMNIA AND GASTROESOPHAGEAL REFLUX DISEASE: COURSE FEATURES, DEVELOPMENT MECHANISMS AND WAYS OF CORRECTION

PUMTS. 2019; 35(3): 62-67.
https://doi.org/10.31071/promedosvity2019.03.062

This paper addresses insomnia as one of relevant comorbid pathologies in gastroesophageal reflux disease (GERD). The main features of insomnia in GERD are: sleep disorders increase with age and affect mostly women; patients have mild and moderate insomnia; according to the PSQI, significant differences were found in severe daytime sleepiness, significant decline of physical component of life quality, GERD symptoms were more explicit in patients with non-erosive reflux disease. The main factors of GERD-caused sleep disorders are reflux, night heartburn, anxiety and depression. Psychosomatic plays an important part. The ways of insomnia correction in GERD are additional intake of proton pump inhibitors in the evening, ramelteon and melatonin. There is a bi-directional relationship between sleep disturbance and GERD symptoms, depression and insomnia.

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